6533b7d0fe1ef96bd125b5f5
RESEARCH PRODUCT
Synthesis and 1H-NMR configurational study of δ3-thiazolines from 2-aza-1,3-dienes
Barluenga JoséJoglar JeśusOrtiz Fernando LópezSantos FusteroCarlón Raquel PérezPeláez Elvirasubject
ChemistryComputational chemistryOrganic ChemistryDrug DiscoveryProton NMRNuclear magnetic resonance spectroscopyBiochemistryTwo-dimensional nuclear magnetic resonance spectroscopydescription
Abstract A [4+1] heterocyclization process involving 2-aza-1,3-dienes and elemental sulphur leading to the synthesis of Δ3-thiazolines with excellent yields is described. A 1D TOCSY and 1D NOESY study of these systems was made in order to establish the configurations of the diastereoisomeric mixture.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1992-01-01 | Tetrahedron |