6533b7d0fe1ef96bd125b631
RESEARCH PRODUCT
5-Carbonyl-1,3-oxazine-2,4-diones from N-Cyanosulfoximines and Meldrum’s Acid Derivatives
Carsten BolmMariela BreguFelix BrosgeKhai-nghi TruongJohannes Florian KochsKari Rissanensubject
Structure analysis010405 organic chemistryOrganic Chemistry010402 general chemistryMeldrum's acid01 natural sciencesBiochemistry0104 chemical scienceschemistry.chemical_compoundchemistryProduct (mathematics)Organic chemistryProduct formationPhysical and Theoretical Chemistrydescription
At elevated temperatures, N-cyanosulfoximines react with Meldrum's acid derivatives to give sulfoximines with N-bound 5-carbonyl-1,3-oxazine-2,4-dione groups. A representative product was characterized by single-crystal X-ray structure analysis. The product formation involves an unexpected molecular reorientation requiring several sequential bond-forming and -cleaving processes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-08-04 | Organic Letters |