6533b7d1fe1ef96bd125bed2

RESEARCH PRODUCT

Long-lasting coma.

Bagnato SBoccagni CSant'angelo AFingelkurts AaFingelkurts AaCesare GagliardoGalardi G

subject

Settore MED/37 - Neuroradiologiaascending reticular activating system (ARAS) coma diagnosis coma pathophysiology coma prognosis disorders of consciousness vegetative state.Settore MED/26 - NeurologiaSettore MED/36 - Diagnostica Per Immagini E Radioterapia

description

n this report, we describe the case of a patient who has remained in a comatose state for more than one year after a traumatic and hypoxic brain injury. This state, which we refer to as long-lasting coma (LLC), may be a disorder of consciousness with significantly different features from those of conventional coma, the vegeta- tive state, or brain death. On the basis of clinical, neu- rophysiological and neuroimaging data, we hypothe- size that a multilevel involvement of the ascending reticular activating system is required in LLC. This description may be useful for the identification of other patients suffering from this severe disorder of con- sciousness, which raises important ethical issues.

http://europepmc.org/abstract/med/25473741