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RESEARCH PRODUCT
Epoxidation of Olefins with a Silica-Supported Peracid in Supercritical Carbon Dioxide under Flow Conditions
Rossella MelloAna Alcalde-aragonésMaría Elena González-núñezGregorio AsensioAndrea Olmossubject
Solventchemistry.chemical_compoundFlow conditionsSupercritical carbon dioxidechemistryReagentOrganic ChemistryCarbon dioxideAnhydrousOrganic chemistryHydrogen peroxidedescription
Anhydrous 2-percarboxyethyl-functionalized silica (2b), a recyclable supported peracid, is a suitable reagent to perform the epoxidation of alkenes 1 in supercritical carbon dioxide at 250 bar and 40 °C under flow conditions. This procedure simplifies the isolation of the reaction products and uses only carbon dioxide as a solvent under mild conditions. The solid reagent 2b can be easily recycled by a reaction with 30% hydrogen peroxide in an acid medium.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-04-27 | The Journal of Organic Chemistry |