6533b7d1fe1ef96bd125ca9f
RESEARCH PRODUCT
The zona incerta system: Involvement in attention and movement
Pierre-yves RisoldSandrine ChomettonMarie Barbiersubject
Subthalamic nucleusmedicine.anatomical_structureCerebral cortexSuperior colliculusBasal gangliamedicineZona incertaCognitionBrainstemBiologyTectumNeurosciencedescription
The zona incerta (ZI) is a large structure made of four neurochemically defined regions (at least, in rodents). It is globally involved in complex connections with telencephalic and brainstem centers. In this work, we focus on some of the anatomical links this structure develops with the cerebral cortex and the tectum. We also point to its integration within a larger basal ganglia network. The functions of this region are still mysterious, even if recent works suggest its participation in behavioral expression. Studies about the functional organization of the vibrissal system have provided the first integrated model, illustrating the ZI's role in sensory-motor programing. In addition, ZI connections with the superior colliculus and the cerebral cortex as well as recent behavioral studies point to this region playing a role in cognitive processes related to attention toward salient stimuli.
year | journal | country | edition | language |
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2021-01-01 |