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RESEARCH PRODUCT
Continuous flow-injection-atomic absorption spectrometric method for the determination of Ondansetron
L. Lahuerta ZamoraJ. Martínez Calatayudsubject
ChromatographyChemistryContinuous flowCalibration curveAnalytical chemistryLead dioxideBiochemistryDosage formAnalytical Chemistrylaw.inventionOndansetronchemistry.chemical_compoundPolymerizationlawmedicineEnvironmental ChemistryAtomic absorption spectroscopyQuantitative analysis (chemistry)Spectroscopymedicine.drugdescription
Abstract A flow-injection procedure for the indirect determination of the new drug Ondansetron is proposed. The method is based on the reaction of the drug in an oxidative solid-phase reactor included in the flow assembly. The reactor was made by lead dioxide physically entrapped by polymerization; the released lead(II) was monitored by atomic absorption spectrometry at 217.0 nm. The procedure gave a linear calibration graph up to 20 μg ml−1 of Ondansetron with a sample throughput of 338 samples h−1.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1995-01-01 | Analytica Chimica Acta |