6533b7d1fe1ef96bd125d4da

RESEARCH PRODUCT

New Acylated Presenegenin Saponins from Two Species ofMuraltia

subject

description

Six new acylated bisdesmosidic triterpene glycosides 1–6 were isolated from the roots of Muraltia heisteria (L.) DC., as three inseparable mixtures 1/2, 3/4, and 5/6 of the (E)- and (Z)-3,4,5-trimethoxycinnamoyl derivatives. The compound pair 1/2 along with four known saponins were also isolated from the roots of Muraltia satureioides DC. Their structures were elucidated mainly by spectroscopic experiments including 2D-NMR techniques as 3-O-(β-D-glucopyranosyl)presenegenin 28-{O-β-D-apiofuranosyl-(13)-O-[β-D-xylopyranosyl-(14)]-O-α-L-rhamnopyranosyl-(12)-O-[6-O-acetyl-β-D-galactopyranosyl-(13)]-4-O-[(E)-3,4,5-trimethoxycinnamoyl]-β-D-fucopyranosyl} ester (1) and its (Z)-isomer 2, 3-O-(β-D-glucopyranosyl)presenegenin 28-{O-6-O-acetyl-β-D-galactopyranosyl-(13)-O-[3-O-acetyl-α-L-rhamnopyranosyl-(12)]-4-O-[(E)-3,4,5-trimethoxycinnamoyl]-β-D-fucopyranosyl} ester (3) and its (Z)-isomer 4, and 3-O-(β-D-glucopyranosyl)presenegenin 28-{O-3-O-acetyl-α-L-rhamnopyranosyl-(12)-O-[β-D-xylopyranosyl-(13)]-4-O-[(E)-3,4,5-trimethoxycinnamoyl]-β-D-fucopyranosyl} ester (5) and its (Z)-isomer 6, respectively.