Truncated internalin A and asymptomatic Listeria monocytogenes carriage: in vivo investigation by allelic exchange

6533b7d1fe1ef96bd125d88f

RESEARCH PRODUCT

Truncated internalin A and asymptomatic Listeria monocytogenes carriage: in vivo investigation by allelic exchange

Dominique Garmyn Pascal Piveteau Jean Guzzo Sandrine Rousseaux Maïwenn Olier Jean-paul Lemaître

subject

Molecular Sequence Data Immunology Virulence Chick Embryo medicine.disease_cause Microbiology Microbiology 03 medical and health sciences Bacterial Proteins Listeria monocytogenes In vivo medicine Animals Humans Internalin Allele Alleles 030304 developmental biology 0303 health sciences Cellular Microbiology: Pathogen-Host Cell Molecular Interactions Base Sequence Virulence biology 030306 microbiology Microbiology and Parasitology bacterial infections and mycoses biology.organism_classification Listeria monocytogenes Virology Microbiologie et Parasitologie In vitro 3. Good health Infectious Diseases Carriage [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology Parasitology Caco-2 Cells Bacteria

description

ABSTRACT Allelic exchange of the region coding for the C terminus of InlA between one epidemic (with an 80-kDa InlA) and one asymptomatic (with a 47-kDa InlA) carriage Listeria monocytogenes strain confirmed the need for this region for internalin entry in vitro. Interestingly, restoration of internalin A functionality did not result in full virulence in chicken embryo assays.

year	journal	country	edition	language
2004-12-25

10.1128/iai.73.1.644-648.2005 https://hal.inrae.fr/hal-02675664

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