6533b7d1fe1ef96bd125d977
RESEARCH PRODUCT
Phytochemical characterization and antioxidant activity of the aerial part extracts from two species of Matthiola wild in Sicily: Matthiola sinuata and M. tricuspidata (Brassicaceae)
Emilia CavòMaria Fernanda TavianoVivienne SpadaroFrancesco Maria RaimondoFrancesco CacciolaYassine Oulad El MajdoubLuigi MondelloFederica DavìConcetta CondursoFabrizio CincottaAntonella VerzeraNatalizia Micelisubject
Sicilian vascular floraArtemia salina bioassaySettore BIO/02 - Botanica Sistematicaantioxidant propertiePlant ScienceSettore BIO/15 - Biologia FarmaceuticaMatthiolabioactive compoundEcology Evolution Behavior and Systematicsdescription
As part of a project aimed at investigating the specific and intraspecific taxa of Matthiola which grow spontaneously in Sicily (Italy), in this work our research has been focused on Matthiola tricuspidata and Matthiola sinuata. The phenolic and volatile compounds of the hydroalcoholic extracts from the aerial parts of the selected species have been characterized by HPLC-PDA/ESI-MS and SPME-GC/MS analyses. Moreover, the antioxidant capacity in vitro (1,1-diphenyl-2-picrylhydrazil (DPPH), reducing power and Fe2+ chelating activity assays) and the toxicity (Artemia salina lethality bioassay) of the extracts were investigated. The phytochemical analyses highlighted quite different phenolic and volatile profiles in the two species. Concerning the antioxidant properties, M. tricuspidata extract resulted the most active both in the DPPH and in the reducing power tests (IC50 = 1.20 ± 0.01 mg/mL and ASE/mL = 11.25 ± 0.97), whereas M. sinuata extract showed better secondary antioxidant properties (IC50 = 1.32±0.02mg/mL). The extracts resulted non-toxic in the Artemia salina lethality bioassay. Our findings indicate that both M. tricuspidata and M. sinuata represent new safe sources of bioactive compounds with antioxidant potential.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-08-05 |