6533b7d2fe1ef96bd125dcbd

RESEARCH PRODUCT

Supported ionic liquid asymmetric cathalysis. A new method for chiral catalyst recycling

Michelangelo GruttadauriaSerena RielaPaolo Maria Giuseppe Lo MeoFrancesca D'annaRenato Noto

subject

aldol reactionSettore CHIM/06 - Chimica Organicaorganocatalysiionic liquid

description

A new method for chiral catalysts recycling, based on the supported ionic liquid asymmetric catalysis concept, has been developed. This concept involves the treatment of a monolayer of covalently attached ionic liquid on the surface of silica gel with additional ionic liquid. These layers serve as the reaction phase in which the homogeneous chiral catalyst is dissolved. As first application of this concept the L-proline-catalyzed aldol reaction has been carried out. Good yields and ee values, comparable with those obtained under homogeneous conditions have been obtained. Moreover, this material shows high regenerability.

yearjournalcountryeditionlanguage
2004-01-01
10.1016/j.tetlet.2004.06.066http://hdl.handle.net/10447/24056