6533b7d2fe1ef96bd125df2c

RESEARCH PRODUCT

The Mechanism of Action of Carbonic Anhydrase

Ivano BertiniJ. M. MoratalLucia BanciClaudio Luchinat

subject

chemistry.chemical_classificationbiologyChemistryCoordination numberCombinatorial chemistryMetalEnzymeMechanism of actionvisual_artCarbonic anhydrasemedicinevisual_art.visual_art_mediumbiology.proteinmedicine.symptom

description

A survey of the structure-function relationship in the enzyme carbonic anhydrase is presented. The coordination number around the metal ion in derivatives inhibited with some anions is stressed as well as the role of the cavity in determining the coordination number. Inferences on the enzyme-substrate interactions are presented.

https://doi.org/10.1007/978-94-009-0663-1_10