6533b7d2fe1ef96bd125dfc5

RESEARCH PRODUCT

Vergleichende dimerisierung der enantiomere von Oct-1-in-3-ol mit chiralen rhodium-phosphan-komplexen

Michael SteigerwaldHellmut Singer

subject

chemistry.chemical_classificationStereochemistryOrganic ChemistryEnantioselective synthesisAlkynechemistry.chemical_elementBond formationBiochemistryRhodiumCatalysisInorganic Chemistrychemistry.chemical_compoundchemistryMaterials ChemistryPhysical and Theoretical ChemistryEnantiomerChirality (chemistry)Phosphine

description

Abstract Three optically active phosphanes ([(S)-2-methylbutyl]3−nP[phenyl]n(n = 0, 1, 2), were tested as ligands in rhodium(I) complexes to form catalysts for the enantioselective dimerisation of (R)- and (S)-oct-1-yn-3-ol. The catalytic reaction provides enantioselectivity for this type of CC bond formation. For reactions at 45–75°C and depending on the P-ligand used the rates vary for both enantiomers from 6:1 to 50:1 in favour of the (S)-octynol.

yearjournalcountryeditionlanguage
1996-02-01Journal of Organometallic Chemistry
https://doi.org/10.1016/0022-328x(95)05845-g