6533b7d2fe1ef96bd125ec76
RESEARCH PRODUCT
Phase-specific modulation of cortical motor output during movement observation.
Alvaro Pascual-leoneFelix M. MottaghyMassimo Gangitanosubject
AdultPremotor cortexPhotic Stimulationmedicine.medical_treatmentMovementStimulationNeuropsychological TestsPremotor cortexMagneticsmedicineHumansEvoked potentialMirror neuronNeuronsHand StrengthGeneral NeuroscienceMotor CortexBody movementEvoked Potentials MotorElectric Stimulationbody regionsTranscranial magnetic stimulationElectrophysiologymedicine.anatomical_structureAcoustic StimulationMirror neuronsArmPsychologyNeurosciencepsychological phenomena and processesTranscranial magnetic stimulationPhotic StimulationPsychomotor Performancedescription
The effects of different phases of an observed movement on the modulation of cortical motor output were studied by means of transcranial magnetic stimulation (TMS). A video-clip of a reaching-grasping action was shown and single TMS pulses were delivered during its passive observation, Times of cortical stimulation were related to the phases of the shown movement, locking them to the appearance of specific kinematic landmarks. The amplitude of the motor evoked potentials (MEPs) induced by TMS in the first dorsal interosseus (FDI) muscle was modulated by the amount of the observed finger aperture. The presence of such an effect is consistent with the notion of a mirror neuron system in premotor areas that couples action execution and action observation also in terms of temporal coding. © 2001 Lippincott Williams & Wilkins.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2001-05-01 | Neuroreport |