ChemInform Abstract: An Efficient Method for the Preparation of Antitumoral α-Keto-imines Benzyldihydroisoquinolines by Selective Benzylic Oxidation with C/Pd in Acetonitrile.

6533b7d2fe1ef96bd125f3c8

RESEARCH PRODUCT

ChemInform Abstract: An Efficient Method for the Preparation of Antitumoral α-Keto-imines Benzyldihydroisoquinolines by Selective Benzylic Oxidation with C/Pd in Acetonitrile.

Ghanem Atassi Pierre Renard Inmaculada Andreu Daniel Henri Caignard Nuria Cabedo Alain Pierre Diego Cortes Almudena Bermejo

subject

chemistry.chemical_compound Chemistry Imine Organic chemistry General Medicine Leukemia L1210 Acetonitrile Combinatorial chemistry In vitro

description

A series of potent antitumor α-keto-imine BDHIQ derivatives were synthesized and assayed in vitro against L1210 leukemia cell line. A new and easy method for the direct formation of α-keto-imine from imine BDHIQ's was performed with 10% C/Pd in acetonitrile.

year	journal	country	edition	language
2010-05-21	ChemInform

https://doi.org/10.1002/chin.200220115

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