6533b7d3fe1ef96bd125fe89
RESEARCH PRODUCT
ChemInform Abstract: A New Versatile Synthesis of N,N′,N′′,N′′′-Tetra(2-carboxyethyl)- and N,N′,N′′,N′′′-Tetra(3-aminopropyl)-tetraazacycloalkanes by Michael Addition of Polyazacycloalkanes to Acrylic Acid and Acrylonitrile.
Roger GuilardH. CholletClaude P. GrosAnil K. Mishrasubject
chemistry.chemical_compoundchemistrybiologyPolymer chemistryMichael reactionTetraGeneral MedicineAcrylonitrilebiology.organism_classificationAcrylic aciddescription
Abstract A smooth and convenient one step synthesis of N,N′,N″,N″′-tetra-(2-carboxyethyl)-tetraazacycloalkanes is reported. These compounds are synthesized by Michael addition of tetraazacycloalkanes to acrylic acid. The same Michael addition of tetraazacycloalkanes to an excess of acrylonitrile also leads to the corresponding tetracyanoethylated derivatives. The reduction of such tetracyanoethylated compounds is a new way of preparation for the corresponding primary amines.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2010-08-05 | ChemInform |