6533b7d3fe1ef96bd12604e5

RESEARCH PRODUCT

HYDROGELS OF HYALURONIC ACID AND alpha, beta-POLYASPARTYLHYDRAZIDE AND THEIR BIOMEDICAL AND PHARMACEUTICAL USES

Gaetano GiammonaGiovanna PitarresiFabio Salvatore Palumbo

subject

Hydrogels hyaluronic acid alpha beta-polyaspartylhydrazide

description

Compositions and products based on the chemical crosslinking of hyaluronic acid with a polyfunctional polymer having a protein-like structure, bearing hydrazido pendent groups along the polymeric chain. The polymer is preferably, alpha-beta-polyaspartylhydrazide, a biocompatible macromolecule. The materials obtained after crosslinking, specifically hydrogels, undergo a reduced chemical and enzymatic degradation, unlike the starting hyaluronic acid, and they can be used to prepare systems for applications in the biomedical and pharmaceutical field.

http://hdl.handle.net/10447/20554