6533b7d3fe1ef96bd126125a
RESEARCH PRODUCT
Surfactant-Induced Helix Formation of Cylindrical Brush Polymers with Poly(L-lysine) Side Chains
Bin ZhangManfred SchmidtYang CongNikhil GunariAndreas JanshoffKarl Fischersubject
chemistry.chemical_classificationPolymers and PlasticsChemistryPrecipitation (chemistry)Organic ChemistryLysineBrushPolymerPolyelectrolytelaw.inventionPulmonary surfactantlawPolymer chemistryHelixMaterials ChemistrySide chaindescription
The complex formation of oppositely charged surfactants with some polypeptides is known to induce β-sheet or helix formation. Here, we report on the complex formation of cylindrical brush polymers with poly(L-lysine) side chains and sodium dodecylsulfate (SDS). With increasing amount of added surfactant the cylindrical polymers first adopt a helical conformation with a pitch of approximately 14-24 nm followed by a spherically collapsed structure before eventually precipitation occurs. CD measurements suggest that the helix formation of the cylindrical brush polymers is driven by the hydrophobicity of the ,8-sheets formed by the PLL side chain-SDS complexes.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2008-05-19 | Macromolecular Rapid Communications |