ChemInform Abstract: Gold(I)-Catalyzed Reactions of 1-(ortho-Alkynylaryl)ureas: Highly Selective Heterocyclization and Synthesis of Mixed N,O-Acetals.

6533b7d3fe1ef96bd12612a4

RESEARCH PRODUCT

ChemInform Abstract: Gold(I)-Catalyzed Reactions of 1-(ortho-Alkynylaryl)ureas: Highly Selective Heterocyclization and Synthesis of Mixed N,O-Acetals.

Gregorio Asensio Mercedes Medio-simón Ana Gimeno Ana B. Cuenca

subject

Chemistry General Medicine Highly selective Medicinal chemistry Catalysis

description

Treatment of alkynylureas (I) with trifluoroethanol in the presence of a Au/Ag catalytic system provides N-6-exo-dig heterocyclization products (III) and in some cases open chain acetals as side products.

year	journal	country	edition	language
2014-07-17	ChemInform

https://doi.org/10.1002/chin.201431173

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