6533b7d3fe1ef96bd12612b6

RESEARCH PRODUCT

Stereoselective Synthesis of β-1-O-Acyl Derivatives of Carbohydrates: An Application of the Cesium Effect.

Richard KullmannHorst KunzJörg ZimmerPeter Wernig

subject

chemistry.chemical_classificationStereochemistryOrganic Chemistrychemistry.chemical_elementBiochemistryAcylationchemistry.chemical_compoundAldosechemistryCaesiumDrug DiscoverySN2 reactionOrganic chemistrylipids (amino acids peptides and proteins)StereoselectivityCarboxylate

description

Abstract The stereoselective formation of anomerically pure 1-O-acyl derivatives of protected carbohydrates is achieved by reaction of the α-glycosyl halogenoses with cesium caboxylates.

https://doi.org/10.1016/0040-4039(92)88116-m