6533b7d3fe1ef96bd126130b

RESEARCH PRODUCT

Autoradiographische Beobachtungen �ber den Einbau von3H-Uridin in herpesinduzierten Riesenzellen

W. PeterknechtDietrich Falke

subject

Giant cellVirologyGeneral MedicineBiologyInhibitory postsynaptic potentialVirologyVirus

description

Cytological studies indicate that Herpes induced polykaryocytes often contain normal appearing nuclei. Further, virus induced DNA-synthesis was absent in about 20% of the nuclei inside of giant cells as observed by autoradiography. On the other hand, RNA-synthesis seems to be inhibited in all nuclei of such cells as evidenced by reduced3H-uridin incorporation. It is concluded that nuclear RNA-synthesis is blocked by spreading of inhibitory factors.

https://doi.org/10.1007/bf01241299