6533b7d4fe1ef96bd12626c1
RESEARCH PRODUCT
THU0598 Course and Predictors of Pain and Physical Functioning in Patients with HIP Osteoarthritis: Systematic Review
Martijn W. HeymansJ.m. DekkerArja HäkkinenLeo D. RoordaCindy VeenhofJasmijn F. M. HollaDiana C. Sanchez-ramirezWillem F. LemsH.c.w. De VetM. Van Der LeedenM. De Rooijsubject
medicine.medical_specialtybusiness.industryImmunologyPatient characteristicsCINAHLGeneral Biochemistry Genetics and Molecular BiologyPhysical medicine and rehabilitationRheumatologyPhysical functioningHomogeneousmedicineHip osteoarthritisPhysical therapyImmunology and AllergyIn patientHealth behaviorbusinessPsychosocialdescription
Background Knowledge of risk factors of future pain and physical functioning can be used to inform patients with hip osteoarthritis (OA) on the likely course of their condition and to adapt treatment according to the prognosis. Objectives To systematically summarise the literature on (1) the course of pain and physical functioning and on (2) prognostic factors of future pain and physical functioning in patients with OA of the hip. Methods A search was conducted in PubMed, CINAHL, Embase, Psych-INFO, and SPORTDiscus up to January 2014. Relevant study characteristics were reviewed. Studies were scored for their quality and a qualitative data synthesis was performed. Results Of the twelve included studies, seven were of high quality. No evidence was found on the course of hip pain, due to a lack of high quality studies. Because of high heterogeneity within studies (reflected by large standard deviations of change scores), the course of physical functioning was interpreted to be indistinct. Clinical characteristics (additional presence of knee OA and higher morbidity count), health behavior factors (no supervised exercise and a lower level of physical activity) and other patient characteristics (lower level of education) (weak evidence) were found to predict future pain (weak evidence). Higher morbidity count and lower vitality were found to predict deterioration in physical functioning (strong evidence). Conclusions The course of physical functioning was found to be highly variable. Several clinical characteristics, health and psychosocial factors prognosticate deterioration of pain and physical functioning in patients with hip OA. These findings may guide future research that aims to identify prognostically homogeneous subgroups of hip OA patients. To our knowledge, this is the first systematic review on prognostic factors for deterioration of pain and physical functioning in patients with hip OA. Disclosure of Interest None declared
year | journal | country | edition | language |
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2015-06-01 | Annals of the Rheumatic Diseases |