6533b7d4fe1ef96bd126306e
RESEARCH PRODUCT
New Triterpenoid and Ergostane Glycosides from the Leaves of Hydrocotyle umbellata L.
Carmelo RosqueteLaurent PouységuLuis B. RojasAdakarleny SosaAdakarleny SosaAdakarleny SosaStéphane QuideauMarie Aleth Lacaille-duboisAnne Claire Mitaine-offerThomas Paululatsubject
chemistry.chemical_classificationErgostanebiologyStereochemistryOrganic ChemistryGlycosideHydrocotyle umbellataMass spectrometrybiology.organism_classificationBiochemistryCatalysisInorganic ChemistryTerpenechemistry.chemical_compoundTriterpenoidchemistryDrug DiscoveryOrganic chemistryPhysical and Theoretical ChemistryOleanolic acidTwo-dimensional nuclear magnetic resonance spectroscopydescription
Two new triterpenoid glycosides, together with two new ergostane glycosides, umbellatosides A–D (1–4, resp.), have been isolated from the leaves of Hydrocotyle umbellata L. Their structures were established by 2D-NMR spectroscopic techniques (1H,1H-COSY, TOCSY, NOESY, HSQC, and HMBC) and mass spectrometry as 3β,22β-dihydroxy-3-O-[α-L-rhamnopyranosyl-(12)-β-D-glucuronopyranosyl]olean-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (1), 3-O-[α-L-rhamnopyranosyl-(12)-β-D-glucuronopyranosyl]oleanolic acid 28-O-β-D-glucopyranosyl ester (2), (3β,11α,26)-ergosta-5,24(28)-diene-3,11,26-triol 3-O-(β-D-glucopyranosyl)-11-O-(α-L-rhamnopyranosyl)-26-O-β-D-glucopyranoside (3), and (3β,11α,21,26)-ergosta-5,24(28)-diene-3,11,21,26-tetrol 3-O-(β-D-glucopyranosyl)-11-O-(α-L-rhamnopyranosyl)-26-O-β-D-glucopyranoside (4).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-10-01 | Helvetica Chimica Acta |