6533b7d4fe1ef96bd12630b1

RESEARCH PRODUCT

Ursane-Type Triterpene Saponins fromZygophyllum geslini

Marie Aleth Lacaille-duboisAnne Claire Mitaine-offerTomofumi MiyamotoDalila SmatiVictoria Hammiche

subject

chemistry.chemical_classificationbiologyOrganic ChemistryGlycosideFraction (chemistry)Zygophyllumbiology.organism_classificationBiochemistryCatalysisInorganic ChemistryTerpenechemistryTriterpeneDrug DiscoveryOrganic chemistryAcid hydrolysisPhysical and Theoretical ChemistryQuinovic acid

description

Four new ursane-based triterpene glycosides, compounds 1–4, as well as the known glycosides zygophylosides E, G, and H, and 3-O-(β-D-quinovopyranosyl)quinovic acid 28-(O-β-D-glucopyranosyl) ester, were isolated from the BuOH-soluble fraction of the MeOH/H2O 7 : 3 extracts of Zygophyllum geslini (roots or aerial parts). Their structures were established mainly by 1D- and 2D-NMR techniques, in combination with HR-MS analysis and acid hydrolysis.

https://doi.org/10.1002/hlca.200790070