ChemInform Abstract: A Non-Catalyzed Ring-Opening Aminolysis Reaction of Sesquiterpene Lactones.

6533b7d4fe1ef96bd126311e

RESEARCH PRODUCT

ChemInform Abstract: A Non-Catalyzed Ring-Opening Aminolysis Reaction of Sesquiterpene Lactones.

Luz Cardona C. L. Garcia José R. Pedro Begoña García Gonzalo Blay

subject

Chemistry General Medicine Ring (chemistry)Sesquiterpene Chloride Pyrrolidine Catalysis Terpene chemistry.chemical_compound Aminolysis medicine Organic chemistry medicine.drug Santonin

description

Abstract Santonin (1) and other sesquiterpene lactones (6–10) react cleanly with pyrrolidine at room temperature to afford γ-hydroxyalkylamides, which by elimination with mesyl chloride in pyridine-benzene at 80°C give unsaturated alkylamides.

year	journal	country	edition	language
2010-08-19	ChemInform

https://doi.org/10.1002/chin.199425195

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