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RESEARCH PRODUCT
HLA-DR phenotypes and blood levels of T cell subsets
Patrizia PalmeriEnrico CillariDomenico LioCalogero Carusosubject
T-LymphocytesT cellImmunologyHLA-DR1 AntigenHistocompatibility Antigens Class IIHLA-DR AntigensGeneral MedicineImmunogeneticsT lymphocyteBiologyBiochemistryPhenotypePeripheral blood mononuclear cellLeukocyte CountHLA-DR3 AntigenPhenotypemedicine.anatomical_structureImmunologyGeneticsmedicineHLA-DRHumansImmunology and AllergyGenedescription
Blood mononuclear cell and T cell subsets values were analyzed in 53 Sicilian individuals according to HLA-DR phenotypes. The results demonstrate that DR1-positive subjects show a significant increase of blood T cell subsets whereas DR3-positive subjects show a non-significant decrease of these values. These results suggest that gene(s) associated with HLA-DR could be one of the factors which affect blood levels of T cell subsets.
year | journal | country | edition | language |
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1984-11-01 | Tissue Antigens |