6533b7d4fe1ef96bd12632e3

RESEARCH PRODUCT

HLA-DR phenotypes and blood levels of T cell subsets

Patrizia PalmeriEnrico CillariDomenico LioCalogero Caruso

subject

T-LymphocytesT cellImmunologyHLA-DR1 AntigenHistocompatibility Antigens Class IIHLA-DR AntigensGeneral MedicineImmunogeneticsT lymphocyteBiologyBiochemistryPhenotypePeripheral blood mononuclear cellLeukocyte CountHLA-DR3 AntigenPhenotypemedicine.anatomical_structureImmunologyGeneticsmedicineHLA-DRHumansImmunology and AllergyGene

description

Blood mononuclear cell and T cell subsets values were analyzed in 53 Sicilian individuals according to HLA-DR phenotypes. The results demonstrate that DR1-positive subjects show a significant increase of blood T cell subsets whereas DR3-positive subjects show a non-significant decrease of these values. These results suggest that gene(s) associated with HLA-DR could be one of the factors which affect blood levels of T cell subsets.

https://doi.org/10.1111/j.1399-0039.1984.tb02145.x