6533b7d4fe1ef96bd126347d

RESEARCH PRODUCT

One-pot synthesis of a new generation of hybrid bisphosphonate polyoxometalate gold nanoparticles as antibiofilm agents

S. TomaneE. López-mayaS. BoujdayV. HumblotJ. MarrotN. RabassoJ. Castells-gilC. SicardA. DolbecqP. MialaneA. Vallée

subject

Materials compostosNanotecnologiaGeneral EngineeringBioengineering02 engineering and technologyGeneral Chemistry[CHIM.MATE]Chemical Sciences/Material chemistry010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesAtomic and Molecular Physics and Optics0104 chemical sciencesGeneral Materials Science0210 nano-technology

description

International audience; A reduced polyoxovanadate functionalized with bisphosphonate molecules was synthesized and used to prepare in one step hybrid organic-inorganic polyoxometalate decorated gold nanoparticles. These new composites were shown to strongly inhibit P. aeruginosa and S. epidermidis biofilms growth, the three components constituting the nanoparticles (Au 0 core, vanadium and alendronate) acting synergistically.

10.1039/c9na00401ghttps://hal.archives-ouvertes.fr/hal-02335689/document