6533b7d5fe1ef96bd1263aa9

RESEARCH PRODUCT

ChemInform Abstract: Synthesis and Antifungal Activity of New N-Isoxazolyl-2-iodobenzamides.

Benedetta MaggioFabiana PlesciaLivio TortaDemetrio RaffaGiuseppe DaidoneDomenico Schillaci

subject

AntifungalPhytophthora citricolabiologymedicine.drug_classfungifood and beverageschemistry.chemical_elementGeneral MedicineIodineReference drugbiology.organism_classificationFungicideAcetic acidchemistry.chemical_compoundchemistrymedicineOrganic chemistryRhizoctonia sp.Botrytis cinerea

description

N-Isoxazolyl-2-iodobenzamides 3 and 9, with a benodanil-like structure, were synthesized by refluxing in acetic acid the corresponding benzotriazinones 2 and 8 with potassium iodide for 1 h with the aim to ascertain if they were active as fungicides against Phytophthora citricola Saw., Botrytis cinerea Pers., Rhizoctonia sp. and Alternaria sp. Among the tested iodo derivatives, compounds 3b and 9a possess interesting activities against the aforesaid fungal strains in several cases similar to that of benodanil I taken as reference drug.

yearjournalcountryeditionlanguage
2010-06-14ChemInform
https://doi.org/10.1002/chin.199931156