6533b7d5fe1ef96bd1263ea9
RESEARCH PRODUCT
Synthesis of oxazolidinones from N-aryl-carbamate and epichlorohydrin under mild conditions
Moreno L. M.Marzullo P.Buscemi S.Insuasty B.Palumbo Piccionello A.subject
toloxatoneOrganic ChemistrycarbamateepichlorohydrinlinezolidSettore CHIM/06 - Chimica OrganicaOxazolidinonedescription
The reaction conditions for an enantiospecific synthesis of various N-aryl-oxazolidinones from N-aryl-carbamates and (R) or (S) epichlorohydrin were optimized. The N-aryl-oxazolidinones were applied to the synthesis of compounds of biological interest such as DuP 721, toloxatone and a linezolid analogue.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-03-02 | Arkivoc |