The mechanism of formation of 3H,9H-Pyrano[3,4-b]indol-3-ones from 3-indolalkanoic acids

6533b7d5fe1ef96bd126467d

RESEARCH PRODUCT

The mechanism of formation of 3H,9H-Pyrano[3,4-b]indol-3-ones from 3-indolalkanoic acids

Houshang Erfanian-abdoust Mercedes Medio-simón Ulf Pindur

subject

chemistry.chemical_classification Acetic anhydride chemistry.chemical_compound Reaction mechanism chemistry Stereochemistry Carboxylic acid Organic Chemistry Lewis acids and bases Physical and Theoretical Chemistry Lactone Mechanism (sociology)

description

The mechanism of the formation of 1-methyl-3H,9H-pyrano[3,4-b]indol-3-one (4) from the corresponding 3-indolacetic acid 1 is discussed. The suggested mechanism is substantiated by the isolation of a stable intermediate 2 and its transformations in the presence of acetic anhydride and/or Lewis acids.

year	journal	country	edition	language
1991-06-13	Liebigs Annalen der Chemie

https://doi.org/10.1002/jlac.1991199101110

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