6533b7d5fe1ef96bd126523f
RESEARCH PRODUCT
Inverted and mirror repeats in model nucleotide sequences.
Fabrizio LilloFabrizio LilloM. Spanòsubject
Independent identically distributedTime FactorsMolecular Sequence DataMarkov processNucleic Acid DenaturationQuantitative Biology - Quantitative MethodsCombinatoricssymbols.namesakeExponential growthChromosomes Human inverted repeatsNucleotideQuantitative Biology - GenomicsRNA Small InterferingQuantitative Methods (q-bio.QM)Sequence (medicine)MathematicsProbabilityRepetitive Sequences Nucleic AcidGenomics (q-bio.GN)chemistry.chemical_classificationStochastic ProcessesModels StatisticalBase SequenceNucleotidesProbabilistic logicMarkov ChainschemistryFOS: Biological sciencesNucleic acidsymbolsNucleic Acid RenaturationNucleic Acid ConformationAlgorithmsdescription
We analytically and numerically study the probabilistic properties of inverted and mirror repeats in model sequences of nucleic acids. We consider both perfect and non-perfect repeats, i.e. repeats with mismatches and gaps. The considered sequence models are independent identically distributed (i.i.d.) sequences, Markov processes and long range sequences. We show that the number of repeats in correlated sequences is significantly larger than in i.i.d. sequences and that this discrepancy increases exponentially with the repeat length for long range sequences.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2007-01-01 | Physical review. E, Statistical, nonlinear, and soft matter physics |