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RESEARCH PRODUCT
ChemInform Abstract: Selective C-H Activation of Methoxy Groups in a Three-Component Photoreaction.
Till OpatzGuenther Lahmsubject
chemistry.chemical_compoundchemistryRadicalPhotocatalysisIminiumGeneral MedicineDimethoxymethaneMedicinal chemistrydescription
Surprisingly, the photocatalytic activation of ethers by H-abstraction and addition of the generated radicals to iminium ions formed in situ from aldehydes and anilines predominantly yielded the products of methoxy activation for dimethoxymethane and 1,2-dimethoxyethane. Various anilines and aromatic as well as aliphatic aldehydes are suitable reaction partners for this three-component photoreaction (Porta-type process) which also provides a simple access to 1,2-aminoalcohols.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-04-01 | ChemInform |