6533b7d6fe1ef96bd1265ae8

RESEARCH PRODUCT

On the Reaction of 3-Bromo-2-nitrobenzo[b]thiophene 13C-Labeled at C-2 with 3-(Trifluoromethyl)aniline:  A Preliminary Insight into a Nucleophilic Substitution with Rearrangement

Domenico SpinelliElvira Di MiceliFrancesco GuerreraAnd Paolo ZaniratoLiliana Lamartina

subject

Substitution reactionTrifluoromethylStereochemistryKornblum–DeLaMare rearrangementfungiOrganic Chemistrybehavioral disciplines and activitiesbody regionschemistry.chemical_compoundchemistryNucleophilic aromatic substitutionparasitic diseasesNitroNucleophilic substitutionThiopheneAcid hydrolysis

description

The results of the title reaction have furnished proofs against a rearrangement of the carbon-atom skeleton and for a nitro group shift in the relevant nucleophilic substitution.

https://doi.org/10.1021/jo962256m