6533b7d6fe1ef96bd1265ba9

RESEARCH PRODUCT

Addition of reducing agent dithiothreitol improves 4-decanolide synthesis by the genus Sporidiobolus.

Charles DivièsGeneviève MauvaisXiao-dong WangRémy CachonGilles Feron

subject

chemistry.chemical_classificationbiologyChemistryReducing agentStereochemistryRicinoleic acidfood and beveragesSubstrate (chemistry)BioengineeringSporidiobolusbiology.organism_classificationApplied Microbiology and BiotechnologyDithiothreitolcarbohydrates (lipids)chemistry.chemical_compoundBiochemistryBiosynthesisGenusLactoneBiotechnology

description

Two species of the genus Sporidiobolus, S. johnsonii and S. ruinenii, were used to study the effect of the reducing agent, dithiothreitol (DTT), on 4-decanolide production using ricinoleic acid as the substrate. The results indicate that the addition of DTT into the cultures significantly enhanced 4-decanolide biosynthesis by the two species.

10.1016/s1389-1723(00)80092-4https://pubmed.ncbi.nlm.nih.gov/16232867