6533b7d6fe1ef96bd12663f6
RESEARCH PRODUCT
�nderungen des Elektrolytgehalts von Erythrocyten und Plasma bei nephrektomierten Ratten
H. BrunnerO. MünchowG KuschinskiG. Peterssubject
medicine.medical_specialtyKidneyChemistrymedicine.medical_treatmentPotassiumchemistry.chemical_elementGeneral MedicineElectrolyteNephrectomyEndocrinologymedicine.anatomical_structureSerum potassiumInternal medicineDrug DiscoverymedicineMolecular MedicineWater-Electrolyte BalanceBlood corpusclesGenetics (clinical)description
After two-stage nephrectomy in rats the potassium concentration in the red blood corpuscles (RBC) decreases from 10.6 ± 0.3 to 5.5 ± 0.3 mEq per 100 ml of RBC within 48 h. The decrease is accompanied by a much smaller increase in the plasma potassium concentration; the hyperkaliemia in nephrectomized rats is less pronounced than in nephrectomized dogs or anuric humans. Na+ in RBC increases by about 44% after nephrectomy; while there is only a very slight decrease of Na+ in plasma. Plasma chlorides drop from 10.92 ± 0.08 mEq/100 ml of plasma to 6.00 ± 0.81 mEq % within 48 h after nephrectomy. RBC chlorides tend to increase again after an initial drop from 5.22 ± 0.07 to 3.82 ± 0.90 mEq% within the first 8 h.
year | journal | country | edition | language |
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1957-02-01 | Klinische Wochenschrift |