6533b7d6fe1ef96bd126676d
RESEARCH PRODUCT
Not just for tumor targeting: unmet medical needs and opportunities for nanomedicine.
Elise LepeltierRudolf ZentelClaus-michael LehrLutz Nuhnsubject
Tumor targetingmedicine.medical_specialtybusiness.industryBiomedical EngineeringCancer therapyMedicine (miscellaneous)Tumor therapyBioengineeringDevelopmentT-Cell EpitopesDrug Delivery SystemsNanomedicineNeoplasmsImmunologymedicineNanomedicineHumansNanoparticlesGeneral Materials ScienceImmunotherapyIntensive care medicinebusinessdescription
During the last 3 decades, nanomedicines have provided novel opportunities to improve the delivery of chemotherapeutics in cancer therapy effectively. However, many principles learnt from there have the potential to be transferred to other diseases. This perspective article, on the one hand, critically reflects the limitations of nanomedicines in tumor therapy and, on the other hand, provides alternative examples of nanomedicinal applications in immunotherapy, noninvasive drug deliveries across epithelial barriers and strategies to combat intra- and extra-cellular bacterial infections. Looking ahead, access to highly complex nanoparticular delivery vehicles given nowadays may allow further improved therapeutic concepts against several diseases in the future too.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-10-01 | Nanomedicine (London, England) |