6533b7d6fe1ef96bd12672b8

RESEARCH PRODUCT

Interleukin 2 Induction in Lyt 1 + 23 − T Cells from Listeria monocytogenes -Immune Mice

Helmut HahnMartin RöllinghoffStefan H. E. KaufmannMarkus M. SimonHermann Wagner

subject

Interleukin 2T-LymphocytesImmunologyBiologymedicine.disease_causeMicrobiologyMicrobiologyMiceImmune systemAntigenListeria monocytogenesRadioresistancemedicineAnimalsAntigens LyMacrophageListeriosisAntigens BacterialMacrophagesListeria monocytogenesPhenotypeIn vitroPhenotypeInfectious DiseasesAntigens SurfaceInterleukin-2Thy-1 AntigensParasitologymedicine.drug

description

Peritoneal exudate T lymphocytes from mice experimentally infected with the intracellular bacterium Listeria monocytogenes secreted high interleukin 2 activities after interaction with syngeneic normal macrophage presenting listerial antigen in vitro. L. monocytogenes -immune cells secreting IL 2 were radioresistant and bore the phenotype Thy 1 + Lyt 1 + 23 − .

https://doi.org/10.1128/iai.37.3.1292-1294.1982