6533b7d7fe1ef96bd1267b6d
RESEARCH PRODUCT
Ventilatory conditioning by self-stimulation in rats: A pilot study
Samia BenammouJean-louis MiramandNicole El-massiouiGuy VardonPierre PerruchetJorge GallegoChantal Pacteausubject
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologyPilot ProjectsStimulationMESH: Rats Sprague-Dawley030204 cardiovascular system & hematologyRats Sprague-Dawley[ SDV.NEU.SC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesSelf Stimulation0302 clinical medicineConditioning PsychologicalMESH: AnimalsMedial forebrain bundleMESH: Self StimulationApplied PsychologyMESH : Reinforcement (Psychology)[SDV.NEU.PC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behaviorMESH : Pilot ProjectsMESH : RatsRespiration[SDV.NEU.SC]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Cognitive SciencesMESH: Reinforcement (Psychology)Quiet wakefulnessNeuropsychology and Physiological Psychologymedicine.anatomical_structure[ SDV.NEU.NB ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologyAnesthesiaBreathingGeneral Agricultural and Biological SciencesPsychologyReinforcement Psychologypsychological phenomena and processesMESH: RatsMESH : Self StimulationCentral nervous systemArousal[ SDV.NEU.PC ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Psychology and behavior03 medical and health sciencesmedicineAnimalsMESH: RespirationMESH: Conditioning (Psychology)MESH: Pilot ProjectsMESH : Rats Sprague-DawleyRatsMESH : RespirationBrain stimulationConditioningMESH : Animals030217 neurology & neurosurgeryMESH : Conditioning (Psychology)description
International audience; This article describes an experimental attempt to condition breathing pattern in rats. In this experiment, a freely moving rat was first rewarded by an electrical stimulation of the medial forebrain bundle whenever inspiratory duration (TI) exceeded 300 ms. A bidirectional control was then used: TIs longer than 400 ms were rewarded, and then TIs shorter than 300 ms were rewarded. The frequency of TIs longer than 300 ms increased when this event was rewarded, further increased when TIs above 400 ms were rewarded, and decreased during reversal conditioning (TI < 300 ms). At the beginning of the experiment, stimulation caused increased arousal and motor activity, but after prolonged conditioning, the brain stimulation was associated with quiet wakefulness. Although the general procedure appears to be well-suited to the experimental study of voluntary breathing, some possible improvements are suggested for further, more extensive investigations.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1994-06-06 | Biofeedback and Self-Regulation |