6533b7d7fe1ef96bd126809a
RESEARCH PRODUCT
G.F.R. measuring with 99mTc-DTPA: limits in obstructive acute renal failure.
L. SalernoB. CurialeS. PepeCorrao SalvatoreD. Mirabilesubject
Settore MED/14 - NefrologiaSettore MED/09 - Medicina InternaAcute Kidney Injury/physiopathology* Female Glomerular Filtration Rate* Humans Middle Aged Technetium Tc 99m Pentetate/diagnostic use*HumansTechnetium Tc 99m PentetateFemaleAcute Kidney InjuryMiddle AgedSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheGlomerular Filtration Ratedescription
After a short introduction on the advantages and limits of G.F.R. determination with Ccr, the radioisotopic methods proposed by Schlegel and Gates for this parameter are described, and as well as ERPF and FF, without blood serial samples being necessary. In a severe renal failure case due to obstruction, the Authors have found a great mismatch in the results between the traditional methods and the radioisotopic ones. After the clinical case description, a possible explanation of this discrepancy is proposed: Schlegel and Gates' methods, which well correlate Ccr in chronic renal failure cases, in severe renal failure on obstructive basis, of recent onset, could not indicate the effective glomerular filtrate, but the nephronic mass, functionally blocked by the endocapsular hypertension secondary to the obstruction, but anatomically unaffected and so recoverable by a timely irradication of the obstruction.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1991-01-01 | Panminerva medica |