6533b7d7fe1ef96bd126814a
RESEARCH PRODUCT
Impact of pericardial effusion on cardiac mechanics in patients with dilated cardiomyopathy
F. ScardullaA. RinaudoC. ScardullaSalvatore Pastasubject
finite element analysis cardiac mechanics cardiomyopathy pericardial effusionSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di Macchinedescription
Dilated cardiomyopathy (CDM) is a degenerative disease of the myocardium accompanied by left ventricular (LV) remodeling, resulting in an impaired pump performance. Differently, pericardial effusion(PE) is a liquid accumulation in the pericardial cavity, which may inhibit blood filling of heart chambers. Clinical evidence show that PE may improve pump performance in patients with CDM. Therefore, this study aims to assess wall stress and global function of patients with CDM, PE as compared to healthy patient. These findings suggests that CDM has an important implication in the mechanical changes of LV and right ventricle by increasing wall stress and reducing pump function. Conversely, PE determines lowering myocardial fiber stress and improves global function as compared to those of CDM
year | journal | country | edition | language |
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2013-01-01 |