6533b7d7fe1ef96bd126814a

RESEARCH PRODUCT

Impact of pericardial effusion on cardiac mechanics in patients with dilated cardiomyopathy

F. ScardullaA. RinaudoC. ScardullaSalvatore Pasta

subject

finite element analysis cardiac mechanics cardiomyopathy pericardial effusionSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di Macchine

description

Dilated cardiomyopathy (CDM) is a degenerative disease of the myocardium accompanied by left ventricular (LV) remodeling, resulting in an impaired pump performance. Differently, pericardial effusion(PE) is a liquid accumulation in the pericardial cavity, which may inhibit blood filling of heart chambers. Clinical evidence show that PE may improve pump performance in patients with CDM. Therefore, this study aims to assess wall stress and global function of patients with CDM, PE as compared to healthy patient. These findings suggests that CDM has an important implication in the mechanical changes of LV and right ventricle by increasing wall stress and reducing pump function. Conversely, PE determines lowering myocardial fiber stress and improves global function as compared to those of CDM

http://www.scopus.com/inward/record.url?eid=2-s2.0-84888417616&partnerID=MN8TOARS