6533b7d7fe1ef96bd126868c

RESEARCH PRODUCT

Making natural products from renewable feedstocks: back to the roots?

Jonathan GroßTill OpatzJonas Kühlborn

subject

ChitinRaw material010402 general chemistryLignin01 natural sciencesBiochemistryNatural (archaeology)chemistry.chemical_compoundDrug DiscoveryLigninBiomassCelluloseCelluloseBiological ProductsChitosanTerpenes010405 organic chemistrybusiness.industryOrganic ChemistryTotal synthesisGreen Chemistry TechnologyPulp and paper industryWoodCarbon0104 chemical sciencesRenewable energychemistryEnvironmental sciencebusinessOils

description

Covering: up to mid-2019 This review highlights the utilization of biomass-derived building blocks in the total synthesis of natural products. An overview over several renewable feedstock classes, namely wood/lignin, cellulose, chitin and chitosan, fats and oils, as well as terpenes, is given, covering the time span from the initial beginning of natural product synthesis until today. The focus is put on the origin of the employed carbon atoms and on the nature of the complex structures that were assembled therefrom. The emerging trend of turning away from petrochemically derived starting materials back to bio-based resources, just as seen in the early days of total synthesis, shall be demonstrated.

https://doi.org/10.1039/c9np00040b