Aktīvo farmaceitisko vielu degradācija ar maiņsprieguma aukstās plazmas avotiem

6533b7d7fe1ef96bd126891f

RESEARCH PRODUCT

Aktīvo farmaceitisko vielu degradācija ar maiņsprieguma aukstās plazmas avotiem

Igors Sušinskis

subject

augstspriegums ultraskaņa koronizlāde reaktors Ķīmija barjerizlāde

description

Aktīvo farmaceitisko vielu degradācija ar maiņsprieguma aukstās plazmas avotiem. Zinātniskais vadītājs: Dr. ķīm., asoc. prof. Pēteris Mekšs, maģistra darbs, 69 lappuses, 28 tabulas, 37 attēli, 61 literatūras avoti, 12 pielikumi. Latviešu valodā. Darba gaitā ir apskatīti dažādu savienojumu degradācijas veidi, izmantojot brīvo radikāļu iegūšanu ar fizikālas iedarbības metodēm. Uzmanība pievērsta dažādiem elektriskās izlādes veidiem, to īpašībām un raksturlielumiem. Salīdzināti tādi izlādes veidi, kā barjerizlāde, koronizlāde, strīmera un dažādu temperatūru izlādes. Aprakstīta augstsprieguma avotu uzbūve un to darbības principi. Eksperimentālajā daļā aprakstīta un izvērtēta dažādu modeļsavienojumu degradācija, izmantojot augstas plazmas avotus: maiņstrāvas koronizlādi un dielektrisko barjerizlādi. Degradācijas produktu analīzei un identificēšanai tika lietota augsti efektīvā šķidrumu hromatogrāfija un gāzu hromatogrāfija ar masas selektīviem detektoriem. Konstruēts reaktora prototips, kurā var degradēt -ūdeni piesārņojošas farmaceitiskas vielas gan šķidrā, gan suspendētā veidā. Vielu degradēšana notiek aerosola veidā, kura iegūšanai izmanti divi ultraskaņas ģeneratori.

year	journal	country	edition	language
2019-01-01

https://dspace.lu.lv/dspace/handle/7/46732

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