6533b7d7fe1ef96bd1268d62
RESEARCH PRODUCT
[a]-Anellated carbazoles with antitumor activity: Synthesis and cytotoxicity
Ulf PindurDieter SchollmeyerG. FischerM. Roggesubject
Antitumor activityHuman tumorChemistryOrganic chemistryGeneral ChemistryCytotoxicitydescription
The cycloadducts3,5, and7, readily available from methoxy-substituted 3-vinylindoles1 and2, were dehydrogenated withDDQ to the coplanar [a]-anellated carbazoles4,6, and8. Compound4a, also characterized by X-ray structural analysis, shows significant cytotoxicity against K562 und RXF393 human tumor cell lines.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1996-01-01 | Monatshefte f�r Chemie Chemical Monthly |