6533b7d7fe1ef96bd1268de9

RESEARCH PRODUCT

A new and versatile method for iodofunctionalization of 1,3-dienes

José BarluengaJosé M. GonzálezGregorio AsensioPedro J. Campos

subject

Addition reactionchemistry.chemical_compoundGeneral methodNucleophileChemistryOrganic ChemistryDrug DiscoveryPyridineHalogenationOrganic chemistryConjugated systemAliphatic compoundBiochemistry

description

Abstract We wish to report the reactions of conjugated dienes with I(py) 2 BF 4 . This simple and general method allows the regiospecific 1,2-addition of iodine and a nucleophile to terminal dienes and the 1,4-addition to internal dienes.

https://doi.org/10.1016/s0040-4039(00)84355-5