Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates

6533b7d7fe1ef96bd126915e

RESEARCH PRODUCT

Targeting Alzheimer’s disease with multimodal polypeptide-based nanoconjugates

Aroa Duro-castano Inmaculada Conejos-sánchez Ana Armiñán M. C. Blanco-gandía Marta Rodríguez-arias Juan R. Viña V. Herranz-pérez Marta Inglés Cristina Mas-bargues María J. Vicent José Miñarro José Manuel García-verdugo Consuelo Borrás

subject

Alzheimer’s disease (AD)Mice Transgenic Nanoconjugates Hippocampal formation Hippocampus Neuroprotection AD treatment Mice 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Alzheimer Disease Bisdemethoxycurcumin Animals Olfactory memory Research Articles 030304 developmental biology 0303 health sciences Amyloid beta-Peptides Multidisciplinary Polyglutamate biology SciAdv r-articles Life Sciences 3. Good health Olfactory bulb Disease Models Animal Applied Sciences and Engineering chemistry biology.protein Neuroscience 030217 neurology & neurosurgery Nanoconjugates Research Article Neurotrophin

description

LRP1-targeted St-Cl–polyglutamate conjugates as multivalent neuroprotective/neurotrophic therapeutics for Alzheimer’s disease.

year	journal	country	edition	language
2021-03-26	Science Advances

https://doi.org/10.1126/sciadv.abf9180

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