6533b7d8fe1ef96bd12697ef

RESEARCH PRODUCT

Polymeric Micelles and Liposomes as Potential Drug Carriers

Helmut RingsdorfM. EmmeliusG. HörpelB. Schmidt

subject

chemistry.chemical_classificationLiposomeEthylene oxidetechnology industry and agriculturemacromolecular substancesPolymerCombinatorial chemistryTransport proteinchemistry.chemical_compoundchemistryAmphiphileCopolymerNanocarriersDrug carrier

description

In the past, a whole aray of polymeric carriers for biologically active substances have been reported. In this field the main interest has focused on the use of randomly solubilized polymers. Naturally occuring amphiphilic transport proteins can be modelled by synthetic micellar solubilized polymers. Poly(ethylene oxide)-polypeptide block copolymers with hydrophobic and cyclophosphamide-containing side groups are described. These micellar systems are able to transport different hydrophobic drugs.

https://doi.org/10.1007/978-1-4613-1809-5_24