6533b7d8fe1ef96bd12697ef
RESEARCH PRODUCT
Polymeric Micelles and Liposomes as Potential Drug Carriers
Helmut RingsdorfM. EmmeliusG. HörpelB. Schmidtsubject
chemistry.chemical_classificationLiposomeEthylene oxidetechnology industry and agriculturemacromolecular substancesPolymerCombinatorial chemistryTransport proteinchemistry.chemical_compoundchemistryAmphiphileCopolymerNanocarriersDrug carrierdescription
In the past, a whole aray of polymeric carriers for biologically active substances have been reported. In this field the main interest has focused on the use of randomly solubilized polymers. Naturally occuring amphiphilic transport proteins can be modelled by synthetic micellar solubilized polymers. Poly(ethylene oxide)-polypeptide block copolymers with hydrophobic and cyclophosphamide-containing side groups are described. These micellar systems are able to transport different hydrophobic drugs.
year | journal | country | edition | language |
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1986-01-01 |