Clinical significance of the polymerase chain reaction (PCR) assay in chronic HBV carriers

6533b7d8fe1ef96bd126ab54

RESEARCH PRODUCT

Clinical significance of the polymerase chain reaction (PCR) assay in chronic HBV carriers

K H Meyer Zum Büschenfelde Michael Manns Marie-anne Petit Patricia Paterlini G. Gerken C. Brechot Dina Kremsdorf

subject

law Genotype Pcr assay virus diseases Clinical significance Hbsag carrier Biology Virology Molecular biology digestive system diseases Polymerase chain reaction law.invention Sequence (medicine)

description

PCR was evaluated as a clinical tool for use in accurate identification of the specific etiologic agent in chronic HBV carriers. The method was found to be valuable in diagnosis and for monitoring therapy, as well as for elucidation of genotypic variants of HBV in chronic HBV cases. By this means an HBV defective variant with alterations in the preSl/preS2 sequence was detected and is consequently described here.

year	journal	country	edition	language
1992-01-01

https://doi.org/10.1007/978-3-7091-5633-9_21

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