6533b7d8fe1ef96bd126ac93

RESEARCH PRODUCT

ChemInform Abstract: Enantioselective Henry Addition of Methyl 4-Nitrobutyrate to Aldehydes. Chiral Building Blocks for 2-Pyrrolidinones and Other Derivatives.

Victor Hernandez‐olmosJosé R. PedroGonzalo Blay

subject

ChemistryEnantioselective synthesisOrganic chemistryGeneral MedicinePyrrolidinonesMethyl 4-nitrobutyratePyrrole derivatives

description

The reaction is applied to a wide range or aromatic and aliphatic aldehydes and proceeds with moderate to good diastereoselectivities.

https://doi.org/10.1002/chin.201046133