6533b7d8fe1ef96bd126af18
RESEARCH PRODUCT
Oncological Outcomes of Primary vs. Salvage OPHL Type II: A Systematic Review
Carmelo SaranitiBarbara VerroFrancesco CiodaroFrancesco Gallettisubject
Salvage TherapyHealth Toxicology and MutagenesisRPublic Health Environmental and Occupational HealthLaryngectomyHead and neck; Laryngectomy; Otolaryngology; Salvage therapy; Surgical oncology; Disease-Free Survival; Humans; Laryngectomy; Neoplasm Recurrence Local; Retrospective Studies; Salvage Therapy; Treatment Outcome; Laryngeal NeoplasmsDisease-Free Survivalhead and necksurgical oncologyNeoplasm RecurrenceTreatment OutcomeSettore MED/31 - OtorinolaringoiatriaLocalotolaryngologyMedicineHumansNeoplasm Recurrence LocalLaryngeal NeoplasmsRetrospective Studiesdescription
Background: Open partial horizontal laryngectomy type II (OPHL type II) has two main aims: oncological radicality and laryngeal preservation. The aim of this review is to define and emphasize the oncological efficacy of OPHL type II, both as primary and salvage surgery, by analyzing the latest literature. Methods: The research was carried out on Pubmed, Scopus and Web of Science databases, by using strict keywords. Oncological outcomes were evaluated by the following parameters: overall survival, disease-specific survival, disease-free survival, local control, laryngeal preservation, local recurrence. Results: The review included 19 articles divided into three groups: (1) primary OPHL type II, (2) salvage OPHL type II, (3) adjuvant radiotherapy after primary OPHL type II. The articles showed excellent results as far as oncological radicality and organ preservation. Conclusions: This review demonstrated that OPHL type II is useful to obtain oncological radicality both as primary surgery and salvage surgery. Nevertheless, the only criterion that determined the positive outcome and efficacy of this technique is the strict selection of patient and tumor.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-02-06 |