6533b7d9fe1ef96bd126b9b1
RESEARCH PRODUCT
Adipose Tissue: ILC2 Crank Up the Heat
Melanie FlachAndreas Diefenbachsubject
medicine.medical_specialtyPhysiologyInnate lymphoid cellInnate immunologyAdipose tissueCell BiologyBiologychemistry.chemical_compoundEndocrinologychemistryAdipocyteInternal medicinemedicineMolecular Biologydescription
White-to-beige conversion of adipocytes is one of the most promising approaches to therapeutically target obesity; however, the signals driving this process had largely remained unclear. Recently, two publications, Brestoff et al. (2014) in Nature and Lee et al. (2015) in Cell, showed that group 2 innate lymphoid cells directly regulate adipocyte differentiation and drive the growth of beige fat.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2015-02-01 | Cell Metabolism |