6533b7d9fe1ef96bd126c39e

RESEARCH PRODUCT

Automatic Location of Sources of Electrical Activation from Electroanatomical Maps

Rafael SebastianIgnacio García-fernándezMiguel LozanoFernando Barber

subject

03 medical and health sciences0302 clinical medicineTree structure0206 medical engineering02 engineering and technology030204 cardiovascular system & hematologyDiscrete setBiological system020601 biomedical engineeringActivation patternMathematics

description

Electro-anatomical mapping is a widely used technique used by electrophysiologists to understand patient's activation pattern. The system measures activation time at different locations but does not provide information on underlying electrical pathways or triggering points, such as Purkinje-myocardial junctions or ectopic foci. We present a method to estimate the locations of Purkinje-myocardial junctions from a discrete set of endocardial samples. Using less than 1000 endocardial samples it can recover locations and activation times of the most influencing Purkinje myocardial junctions from Purkinje trees of up to 500 junctions. A simulation study revealed that using the estimated Purkinje myocardial junctions, mean squared errors of local activation times remain low for different tree structures.

https://doi.org/10.22489/cinc.2016.128-255